Argentina faces a significant healthcare challenge as a substantial number of its population grapples with chronic kidney disease of unknown origin (CKDUO), making it the third leading cause for dialysis admissions. This trend highlights critical gaps in early diagnosis and accessible kidney care across the nation.
Demographic Shifts in Dialysis Patients
From April 2004 to December 2021, over 113,000 Argentine patients began maintenance dialysis, with a notable 42% aged above 65 and a small fraction under 18. The patient base predominantly consists of males, accounting for nearly 59%, and includes a 6% representation of foreign nationals. These statistics underscore the diverse demographic impacted by kidney failure in Argentina.
Diagnostic Challenges and Treatment Modalities
A mere 9.4% of dialysis patients received a kidney biopsy for diagnostic confirmation, indicating limited access to essential diagnostic procedures. Diabetic nephropathy leads as the primary cause of kidney failure, followed by hypertensive nephropathy and CKDUO. Hemodialysis emerges as the preferred treatment method, with most patients starting treatment using temporary vascular access, reflecting systemic constraints in managing chronic kidney disease effectively.
– CKDUO patients tend to be younger and predominantly female.
– Socioeconomic disparities contribute to delayed kidney health assistance.
– Regional variations in renal biopsy rates highlight uneven healthcare resource distribution.
– Longer survival rates observed in CKDUO patients compared to others.
The study reveals that individuals with CKDUO generally enjoy a longer survival duration post-dialysis initiation, averaging nearly 59 months compared to 48 months for other causes. However, these patients often come from more vulnerable socioeconomic backgrounds and receive inadequate early renal care, exacerbating their condition’s progression.
Addressing the rising incidence of CKDUO requires comprehensive health policies focused on enhancing early detection and expanding access to kidney health services. Ensuring equitable distribution of diagnostic tools and resources across all regions can mitigate the disparities evident in current dialysis admissions and improve overall patient outcomes.
Expanding kidney health accessibility early in chronic kidney disease can not only reduce the demand for dialysis but also enhance the quality of life for those affected. Implementing targeted health initiatives and investing in diagnostic infrastructure are pivotal steps toward combating the growing burden of kidney failure in Argentina.

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