A recent multinational study reveals that increasing periods of effective symptom control, known as ‘Good ON-time’ (GOT), significantly benefits individuals battling advanced Parkinson’s disease (aPD). This research highlights how even incremental improvements in GOT can lead to better clinical outcomes, enhanced quality of life, and reduced healthcare costs.
Study Insights Across Seven Countries
Analyzing data from 802 aPD patients across seven nations, researchers utilized the Adelphi Parkinson’s Disease Specific Program survey conducted between 2017 and 2020. The study calculated GOT by assessing self-reported periods of symptom control without debilitating dyskinesia within a standardized 16-hour day. Various factors such as symptom management, medication usage, fall incidents, daily living activities, quality of life, and healthcare resource utilization were meticulously examined.
Significant Benefits of Increased GOT
Findings indicate that each additional hour of GOT correlates with a decrease in uncontrolled motor and non-motor symptoms. Patients reported needing fewer medication classes and experienced a lower risk of falls. Moreover, greater independence in daily activities and an improved quality of life were directly associated with extended GOT periods.
Key Inferences:
- Enhanced GOT leads to fewer uncontrolled symptoms and reduced reliance on multiple medications.
- Patients experience lower fall risks and greater independence in daily activities.
- Extended GOT contributes to significant healthcare cost savings annually.
The economic analysis revealed that each additional hour of GOT could save approximately $8,602 per patient annually in healthcare resources. This underscores the financial viability of interventions aimed at increasing GOT among aPD patients.
Effective management strategies that prioritize extending GOT can profoundly impact the well-being of those with advanced Parkinson’s disease. By focusing on treatments that enhance symptom control without adverse effects, healthcare providers can improve patient outcomes and reduce economic burdens.
Facilitating longer periods of good symptom control not only elevates the quality of life for patients but also alleviates the strain on healthcare systems. Future therapeutic approaches should consider these findings to optimize treatment plans and support sustained patient health and independence.
This article has been prepared with the assistance of AI and reviewed by an editor. For more details, please refer to our Terms and Conditions. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author.
