Wednesday, April 30, 2025

Can NICE Decision Outcomes Influence Global HTA Decision-Making?

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In a recent study, using both quantitative and qualitative methods, the level of influence and the potential mechanisms involved were assessed. findings suggest that NICE decisions do affect healthcare decisions in most countries studied, although the nature and extent of this influence vary widely.

Negative NICE decisions tend to have a more significant international impact compared to positive ones. Local decision-makers may closely examine the evidence presented and leverage negative decisions to negotiate lower prices. However, the future impact of NICE on the global Health Technology Assessment (HTA) landscape could change due to increased collaboration among HTA agencies and the adoption of European regulations on HTA.

HTA plays a crucial role in healthcare decision-making in many countries, with implications for population health. NICE, in particular, holds a prominent position in the global HTA landscape. Yet, limited evidence exists regarding the extent of NICE’s influence and how its decisions affect HTA in other countries. data on NICE HTA decisions and conducted interviews with industry experts, decision-makers, and academics to assess this impact were collected.

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In conclusion, NICE guidance does exert some influence in other countries, serving as background information, scrutinizing assumptions in economic models, or impacting price negotiations. Indirect mechanisms of influence, such as shared methodologies and the reputation of NICE and UK universities, also play a role. The future role of NICE on the international stage may evolve with increased collaboration among HTA agencies and changes in post-Brexit activities, potentially strengthening or weakening its influence, depending on various factors.


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