Anxiety medication prescriptions in Croatia have surged significantly between 2006 and 2022, highlighting shifts in healthcare practices and insurance coverage. This increase occurs alongside a notable reduction in overall spending on these medications, raising questions about prescribing behaviors and regulatory oversight.
Prescription Trends and Cost Analysis
Data reveals that the consumption of anxiolytic drugs climbed from 61.13 DDD per 1000 inhabitants in 2006 to 82.78 DDD per 1000 in 2022, marking a 35.42% rise. Interestingly, the financial expenditure on these medications dropped by 15.57% during the same period. Diazepam emerged as the most prescribed anxiolytic, with prescriptions increasing by 67.42%. Alprazolam usage also saw the highest growth, despite a decline in its private prescription share from 21.22% in 2011 to 16.53% in 2022, suggesting a shift towards insurance-covered prescriptions.
Private Prescriptions and Regulatory Needs
The study highlights a high prevalence of private prescriptions for anxiolytics among patients covered by the Croatian Health Insurance Fund (CHIF). Despite clinical guidelines advising against frequent use or questioning the efficacy of certain anxiolytics, their prescription remains commonplace. This trend underscores the necessity for a more robust national regulatory framework to oversee the prescribing practices of these medications.
• The 35.42% increase in anxiolytic usage indicates rising anxiety levels or changing medical practices.
• The 15.57% decrease in financial expenditure suggests effective cost-containment measures by insurers.
• The significant rise in diazepam and alprazolam prescriptions may reflect their accessibility or perceived efficacy.
• The shift from private to insurer-covered prescriptions could influence patient access and medication adherence.
Enhancing regulatory measures could ensure that anxiolytic prescribing aligns with clinical guidelines, potentially improving patient outcomes and optimizing healthcare spending. Healthcare providers may need further training on alternative treatments for anxiety to reduce dependency on medication. Additionally, patient education on the appropriate use of anxiolytics could play a critical role in addressing the underlying causes of increased prescriptions.

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