The COVID-19 pandemic has significantly disrupted the lives of women battling early-stage hormone-receptor-positive breast cancer. Recent research highlights a troubling decline in adherence to one-year adjuvant endocrine therapy (AET) among this group, closely linked to pandemic-induced hardships.
Economic Challenges Affect Treatment Consistency
A study analyzing data from the THRIVE trial, which monitored AET adherence through electronic pillboxes, revealed that nearly 40% of participants experienced some form of pandemic-related hardship. Financial losses were reported by over a third of the women, while gaps in health insurance and difficulties in accessing basic necessities were also prevalent. These economic strains have directly impacted the ability of patients to maintain their prescribed treatment regimens.
Health Outcomes Tied to Adherence Levels
The research indicates a stark contrast in AET adherence rates between those facing hardships and those who did not. Only 40.1% of women experiencing financial or access-related difficulties adhered to their AET protocols, compared to 59.5% of their less-impacted counterparts. This reduction in adherence poses serious risks for cancer progression and overall survival rates.
- Lower-income patients are disproportionately affected by treatment adherence issues.
- Prior chemotherapy or radiation increases the likelihood of experiencing pandemic-related hardships.
- Economic instability may lead to interruptions in essential cancer therapies.
Addressing these challenges requires a multifaceted approach. Financial screening should become a routine part of patient assessments to identify those at risk of falling behind in their treatments. Additionally, targeted support services, such as financial counseling and assistance programs, can help mitigate the impact of economic hardships on treatment adherence.
Enhancing support systems for breast cancer patients is crucial, especially for those with limited financial resources or those undergoing intensive treatments like chemotherapy and radiation. By implementing comprehensive support measures, healthcare providers can help ensure that all patients have the necessary resources to adhere to their prescribed therapy, ultimately improving health outcomes and survival rates.
The findings underscore the critical intersection between economic stability and healthcare outcomes. As the pandemic continues to affect various aspects of life, proactive measures are essential to safeguard the health of vulnerable cancer patients. Investing in support infrastructures not only aids in treatment adherence but also fosters a more resilient healthcare system capable of withstanding future challenges.

This article has been prepared with the assistance of AI and reviewed by an editor. For more details, please refer to our Terms and Conditions. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author.