The Innovations Committee at the Joint Federal Committee has issued new transfer decisions for completed healthcare projects, now published on their website. The AMSeC project developed a mathematical model to study the effectiveness of booster vaccinations against meningococcal disease. The REDARES project tested support offers for medical practices, successfully promoting guideline-compliant antibiotic prescriptions for uncomplicated urinary tract infections. Results from the ZSE-DUO project demonstrate that a dual pilot structure with psychiatric and somatic specialists can improve diagnostics and care in centers for rare diseases.
The committee is now forwarding these project results to relevant institutions, ensuring that the innovative findings are effectively communicated to those who can implement them in clinical practice. By doing so, they aim to enhance the overall quality of healthcare services. Feedback on how these findings will be used to improve healthcare will also be published on their website, providing transparency and encouraging broader adoption of these practices. This process not only highlights the committee’s commitment to continuous improvement but also supports the dissemination of valuable research outcomes to a wider audience.
Meningococcal diseases are rare but can have severe outcomes. In Germany, serogroups B and C are the most common; vaccinations for children are recommended by the Standing Committee on Vaccination (STIKO) at the Robert Koch Institute. The AMSeC project revealed that the protection against meningococcal C decreases a few years after the initial vaccination.
Combination Vaccine for Adolescents and REDARES Project Improve Healthcare Practices
Using a newly developed dynamic transmission model, researchers simulated whether a booster shot during adolescence with either a monovalent vaccine against meningococcal type C or a combination vaccine against subtypes A, C, W and Y would be beneficial and cost-effective. Results favored the combination vaccine and a booster at ages 13 to 14. The Innovations Committee believes this model can help STIKO decide on adolescent booster vaccinations.
Urinary tract infections (UTIs) are among the most common bacterial infections, usually treated with antibiotics. However, second-line antibiotics are sometimes used contrary to guidelines, which recommend them only for rare, severe infections or complications. The REDARES project examined antibiotic prescribing behaviors for uncomplicated UTIs. General practices received multimodal support, including feedback on their prescribing habits, regional resistance data, and patient information materials.
A process analysis evaluated the feasibility and acceptance of these measures in practice. The project demonstrated that these supports reduced second-line antibiotic prescriptions and overall antibiotic use for uncomplicated UTIs.The committee’s decision to forward project results to relevant institutions aims to facilitate the integration of these findings into healthcare practices.
Transparent Updates on Healthcare Projects Promote Improvement and Accountability
Feedback on the implementation and impact of these projects will be made available on the committee’s website. This transparency ensures continuous improvement in the quality and cost-effectiveness of healthcare services. Additionally, regular updates will be provided to track progress and outcomes, fostering a culture of accountability and ongoing refinement. By making this information publicly accessible, the committee encourages widespread adoption and adaptation of successful practices, ultimately benefiting a larger patient population and enhancing overall healthcare standards.
The National Action Alliance for People with Rare Diseases advocates for specialized centers to care for affected individuals. A key task of these centers is to establish cross-disease structures and processes for diagnosing unclear conditions suspected to be rare diseases. Complex symptom patterns pose particular challenges. The ZSE-DUO project tested a dual pilot structure at these centers, involving both somatic and psychiatric/psychosomatic specialists. These pilots guided patients through the diagnostic process. The evaluation showed that the proportion of patients receiving a diagnosis within twelve months of their first visit significantly increased with the dual pilots’ help.
The committee’s decision to forward project results to relevant institutions aims to facilitate the integration of these findings into healthcare practices. Feedback on the implementation and impact of these projects will be made available on the committee’s website. This transparency ensures continuous improvement in the quality and cost-effectiveness of healthcare services. Additionally, regular updates will be provided to track progress and outcomes, fostering a culture of accountability and ongoing refinement. By making this information publicly accessible, the committee encourages widespread adoption and adaptation of successful practices, ultimately benefiting a larger patient population and enhancing overall healthcare standards.
Resource: Gemeinsame Bundesausschuss, May 17, 2024

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