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Survival Outcomes and Treatment Patterns for Elderly Gastric Cancer Patients in Korea

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Gastric cancer in Korea was the focus of a comprehensive study by the Korea Health and Medical Research Institute (NECA), which released findings examining treatment patterns and survival outcomes among elderly patients, aiming to address the lack of data and treatment guidelines for this demographic. The study analyzed data from 36,099 patients aged 75 or older, revealing that gastrectomy and endoscopic submucosal dissection (ESD) were the primary treatment options, with chemotherapy and radiotherapy less commonly used. However, a significant portion of patients, particularly those with primary metastatic gastric cancer, did not receive treatment after diagnosis.

Analysis of survival outcomes demonstrated that patients who underwent appropriate treatment for localized and locally advanced gastric cancer had lower mortality risks compared to untreated patients. Specifically, those who received ESD or surgical treatment showed significantly lower mortality risks than the untreated group. Conversely, patients with primary metastatic gastric cancer who underwent surgical treatment, chemotherapy, or radiotherapy exhibited lower mortality risks, although overall survival rates remained relatively low.

NECA Study Shows Better Survival Outcomes for Elderly Gastric Cancer Patients

Further investigation comparing ESD and gastrectomy efficacy in early gastric cancer patients aged 75 or older revealed that ESD was associated with a lower mortality risk compared to gastrectomy. Additionally, elderly patients with gastric cancer confined to the mucosa and submucosa showed a higher risk of death with gastrectomy compared to ESD. These findings underscore the importance of considering active treatment options and individual patient factors when managing elderly patients with gastric cancer.

NECA, the Korea Health and Medical Research Institute, underscores the pressing need for the provision of timely and robust scientific evidence to inform the decision-making processes pertinent to elderly patients confronting the complexities of gastric cancer. With the demographic landscape of Korea rapidly transitioning towards an aging society, the burden of gastric cancer among the elderly populace looms large, accentuating the significance of this comprehensive study. By meticulously examining treatment patterns and prognosis among this demographic cohort, the study not only fills critical data gaps but also lays the foundation for the formulation of tailored treatment guidelines.

Survival Outcomes

NECA Study Highlights Survival Outcomes and Efficacy of ESD and Surgery

In shedding light on the effectiveness of various treatment modalities, particularly endoscopic submucosal dissection (ESD) and surgical interventions, in managing gastric cancer among the elderly in Korea, the study’s findings hold profound implications. They underscore the pivotal role of evidence-based research in shaping clinical practice paradigms and facilitating superior patient outcomes. By elucidating the mortality risks associated with different treatment approaches, the study empowers healthcare practitioners with invaluable insights, enabling them to navigate the complexities of treatment decisions with heightened precision and efficacy.

Moreover, NECA accentuates the transformative potential of this study in not only augmenting the current understanding of gastric cancer management but also catalyzing substantive advancements in clinical care frameworks. By corroborating the efficacy of ESD and surgical interventions in mitigating mortality risks among elderly gastric cancer patients, the study reaffirms the indispensable role of evidence-driven insights in optimizing treatment protocols and fostering personalized care pathways.

In essence, the study serves as a beacon of empirical rigor and clinical relevance, heralding a new era of evidence-based decision-making in the realm of gastric cancer management. Its profound impact extends beyond the confines of academic discourse, permeating clinical practice landscapes and ushering in a paradigm shift towards patient-centric care delivery models characterized by heightened efficacy, precision, and outcomes optimization.


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Resource: Korea Health and Medical Research Institute, June 06, 2024

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