Saturday, June 22, 2024

Web-Based Psychological Intervention Proves Cost-Effective for Depressive Symptoms in T2DM Patients

Similar articles

Managing depressive disorder in individuals with type 2 diabetes mellitus (T2DM) poses significant challenges in primary care settings due to resource limitations and difficulties in accessing in-person treatments. Depression can adversely affect various life aspects, including adherence to medical treatments and glycemic control, leading to potential complications and increased healthcare costs. To address these issues, this study explored the efficacy and cost-effectiveness of a web-based psychological intervention for mild-to-moderate depressive symptoms in T2DM patients, offering a promising alternative to traditional treatment as usual (TAU).

Study Design and Methodology

A multicenter randomized controlled trial included 49 patients with T2DM and moderate depressive symptoms, who were divided into two groups: TAU (n=27) and a web-based psychological treatment group (n=22). The web-based intervention incorporated cognitive behavioral therapy (CBT), diabetes self-care improvement, and mindfulness techniques. The primary outcome was the reduction in depressive symptoms measured by the Patient Health Questionnaire-9 (PHQ-9), while secondary outcomes included glycemic control evaluated by reductions in glycosylated hemoglobin (HbA1c) levels. Follow-ups were conducted at 3 and 6 months.

Results and Implications

The web-based intervention demonstrated superior efficacy in reducing depressive symptoms compared to TAU, with incremental cost-effectiveness ratios of 186.76 for a 3-point reduction and 206.31 for reductions of 5 and 50 percentage points on the PHQ-9. However, the improvement in HbA1c was marginal, with an incremental cost-effectiveness ratio of €1510.90 per participant. The cost-utility analysis indicated €4119.33 per quality-adjusted life year gained, underscoring the economic efficiency of the web-based intervention.

User-Usable Inferences

  • The web-based intervention can be a viable alternative for managing depressive symptoms in T2DM patients, especially when traditional face-to-face treatments are inaccessible.
  • Incorporating CBT, diabetes self-care, and mindfulness into eHealth platforms can enhance both clinical outcomes and cost-effectiveness.
  • Future eHealth interventions should include personalized modules to improve diabetes self-care behaviors, addressing the unique needs of T2DM patients.

The study concludes that utilizing web-based modules with integrated CBT, diabetes self-care, and mindfulness effectively reduces depressive symptoms and marginally improves glycemic control in T2DM patients. The intervention not only demonstrates clinical efficacy but also offers economic benefits, supporting eHealth as a cost-effective strategy for healthcare systems. Emphasizing the inclusion of diabetes self-care enhancement modules in future web-based psychological treatments could further personalize and adapt these interventions for this specific population.

Original Article: JMIR Mhealth Uhealth. 2024 May 16;12:e55483. doi: 10.2196/55483.

Subscribe to our newsletter

To be updated with all the latest news, offers and special announcements.

Latest article